The trade: Different divisions, so this is the trade, not a verdict. Unusually, the pill loses more here (11% vs 8%). Oral semaglutide 25 mg adds convenience: a daily pill instead of a once weekly injection, no cold chain. Oral semaglutide 25 mg has its own catch: it must be taken fasting. The pill both loses more and skips the needle, so the trade favours Oral semaglutide 25 mg for most; the injection's case would rest on factors outside these two axes.